diff --git a/Lib/test/test_bytes.py b/Lib/test/test_bytes.py
index 643ac188b..1e1b484c6 100644
--- a/Lib/test/test_bytes.py
+++ b/Lib/test/test_bytes.py
@@ -157,7 +157,6 @@ class BaseBytesTest:
 
         self.assertEqual(self.type2test(B(b"foobar")), b"foobar")
 
-    @unittest.skip("TODO: RUSTPYTHON")
     def test_from_ssize(self):
         self.assertEqual(self.type2test(0), b'')
         self.assertEqual(self.type2test(1), b'\x00')
diff --git a/vm/src/obj/objbyteinner.rs b/vm/src/obj/objbyteinner.rs
index 47bceeb0c..364317986 100644
--- a/vm/src/obj/objbyteinner.rs
+++ b/vm/src/obj/objbyteinner.rs
@@ -82,9 +82,19 @@ impl ByteInnerNewOptions {
             let value = if let OptionalArg::Present(ival) = self.val_option {
                 match_class!(match ival.clone() {
                     i @ PyInt => {
-                        let size = objint::get_value(&i.into_object())
-                            .to_usize()
-                            .ok_or_else(|| vm.new_value_error("negative count".to_owned()))?;
+                        let size =
+                            objint::get_value(&i.into_object())
+                                .to_isize()
+                                .ok_or_else(|| {
+                                    vm.new_overflow_error(
+                                        "cannot fit 'int' into an index-sized integer".to_owned(),
+                                    )
+                                })?;
+                        let size = if size < 0 {
+                            return Err(vm.new_value_error("negative count".to_owned()));
+                        } else {
+                            size as usize
+                        };
                         Ok(vec![0; size])
                     }
                     _l @ PyString => {